History of Insulin Potentiation Therapy

Put simply, chemotherapy drugs have to get inside cancer cells to kill them. Conventionally, this is achieved by using high doses of these drugs, leading to very undesirable and sometimes even fatal side effects. One of the little known facts about cancer cells is that they make their own insulin in order to obtain glucose-the fuel they need in large amounts as they grow and divide at an abnormally rapid rate. We take advantage of insulin’s action. By giving cancer cells insulin, we prime the membranes to open up. Coordinating this event with the introduction of low-doses of chemotherapy, we get much more of the chemotherapy drugs inside the cancer cells to kill them, leaving healthy cells unharmed. This process allows us to avoid dangerous, undesirable dose-related side effects. Described in technical terms, Insulin Potentiation Therapy (IPT) manipulates the mechanisms of malignancy to therapeutic advantage by employing insulin as a biologic response modifier of